Surviving Blood Plague
In addition to the obvious threats of hungry zombies and starvation, State of Decay 2 presents your survivors with a virulent disease called Blood Plague. This illness is transmitted by certain zombies, which can be identified by their red, bloody appearance, or by damaged Plague Hearts defending themselves against your attacks. When one of these plague zombies strikes or bites a survivor, that character begins to contract Blood Plague. This is shown by an “infection meter” that appears above your Health and Stamina meters in the HUD.
If your survivor continues to battle plague zombies and Plague Hearts, this plague meter will continue to fill up. Should this meter become completely full, the survivor contracts full-blown blood plague and has only a limited time left to live. Before reaching that point, visit your Infirmary and use the ‘Infection Therapy’ action to remove the partial infection. This costs a few plague samples, which you can collect from slain plague zombies. Alternatively, you can let a partially infected survivor rest in the infirmary to rid themselves of their sickness.
Once you have contracted blood plague, the only means of removing it is to craft and consume a dose of plague cure. This method is expensive, costing both meds and plague samples. If you don’t have the resources, your options include checking the sick character into your Infirmary (where they’ll be stable but unavailable for use), exiling them, or euthanizing them. Blood plague is a remorseless killer, which is why your survivors are focused on ridding the town of this menace.